Matt Ryan and Drew Brees have faced each other 22 times, the most in NFL history between two QBs.

RYAN BREES
9 wins 13 wins
6,536 yds 6,901 yds
41 td 42 td
14 int 25 int pic.twitter.com/lOZ24XHzLI

— Kevin Keneely (@KevinKeneely1) November 10, 2019